Cajun Chicken Penne Pasta is a delightful dish that brings the vibrant flavors of Louisiana right to your dinner table. This recipe combines tender chicken, perfectly cooked penne pasta, and a medley of spices that create a symphony of taste and texture. Originating from the rich culinary traditions of Cajun cuisine, this dish reflects the cultural melting pot of the South, where French, Spanish, and African influences come together to create something truly special.
People love Cajun Chicken Penne Pasta not only for its bold flavors but also for its convenience. It’s a one-pot meal that can be prepared in under 30 minutes, making it perfect for busy weeknights or casual gatherings with friends. The creamy sauce envelops the pasta and chicken, providing a satisfying comfort that warms the soul. Whether you’re a fan of spicy food or simply looking to try something new, this dish is sure to impress and become a staple in your culinary repertoire.

Ingredients:
- 8 ounces penne pasta
- 2 tablespoons olive oil
- 1 pound boneless, skinless chicken breasts, cut into bite-sized pieces
- 2 teaspoons Cajun seasoning
- 1 teaspoon garlic powder
- 1 teaspoon onion powder
- 1/2 teaspoon smoked paprika
- 1/2 teaspoon salt
- 1/4 teaspoon black pepper
- 1 medium onion, diced
- 1 red bell pepper, diced
- 1 green bell pepper, diced
- 3 cloves garlic, minced
- 1 cup heavy cream
- 1 cup chicken broth
- 1 cup grated Parmesan cheese
- 1/4 cup fresh parsley, chopped (for garnish)
Preparing the Pasta
- Bring a large pot of salted water to a boil over high heat.
- Add the penne pasta to the boiling water and cook according to package instructions until al dente, usually about 10-12 minutes.
- Once cooked, reserve 1/2 cup of the pasta water, then drain the pasta in a colander and set aside.
Preparing the Chicken
- In a large mixing bowl, combine the chicken pieces with Cajun seasoning, garlic powder, onion powder, smoked paprika, salt, and black pepper. Toss until the chicken is evenly coated with the spices.
- Heat 2 tablespoons of olive oil in a large skillet over medium-high heat.
- Add the seasoned chicken to the skillet in a single layer. Cook for about 5-7 minutes, stirring occasionally, until the chicken is browned and cooked through. The internal temperature should reach 165°F (75°C).
- Once cooked, remove the chicken from the skillet and set aside on a plate.
Sautéing the Vegetables
- In the same skillet, add the diced onion, red bell pepper, and green bell pepper. Sauté for about 4-5 minutes, or until the vegetables are softened and the onion is translucent.
- Add the minced garlic to the skillet and cook for an additional 1-2 minutes, stirring frequently to prevent burning.
Making the Sauce
- Pour in the heavy cream and chicken broth into the skillet with the sautéed vegetables. Stir well to combine.
- Bring the mixture to a gentle simmer, allowing it to cook for about 3-4 minutes. This will help the flavors meld together.
- Gradually add the grated Parmesan cheese to the sauce, stirring continuously until the cheese is melted and the sauce is creamy. If the sauce is too thick, add a little of the reserved pasta water until you reach your desired consistency.
Combining the Ingredients
- Add the cooked chicken back into the skillet, stirring to coat it in the creamy sauce.
- Next, add the drained penne pasta to the skillet. Toss everything together until the pasta is well coated with the sauce and all ingredients are evenly distributed.
- Cook for an additional 2-3 minutes over low heat, allowing the pasta to absorb some of the sauce and heat through.
Serving the Dish
- Once everything is heated through, remove the skillet from the heat.
- Serve the Cajun Chicken Penne Pasta hot, garnished with freshly chopped parsley for a pop of color and added flavor.
- For an extra touch, you can sprinkle additional Parmesan cheese on top before serving.
Tips for Perfect Cajun Chicken Penne Pasta
- For a spicier dish, consider adding a pinch of cayenne pepper or using a spicier Cajun seasoning blend.
- Feel free to customize the vegetables based on your preference. Zucchini, mushrooms, or spinach can be great additions.
- If you want to make this

Conclusion:
In summary, this Cajun Chicken Penne Pasta recipe is a must-try for anyone looking to elevate their weeknight dinners with a burst of flavor and a touch of spice. The combination of tender chicken, perfectly cooked penne, and a creamy, zesty sauce creates a dish that is not only satisfying but also incredibly delicious. Whether you’re serving it for a family gathering, a cozy date night, or simply treating yourself, this recipe is sure to impress. For a delightful twist, consider adding sautéed bell peppers or spinach for extra color and nutrition. You can also swap the chicken for shrimp or even a plant-based protein to cater to different dietary preferences. Pair this dish with a crisp green salad and some garlic bread for a complete meal that will leave everyone asking for seconds. We encourage you to try this Cajun Chicken Penne Pasta recipe and make it your own! Don’t forget to share your experience and any variations you come up with. Your feedback and creativity can inspire others to dive into this flavorful dish. Happy cooking! PrintCajun Chicken Penne Pasta: A Spicy and Flavorful Recipe to Savor
Enjoy a creamy Cajun Chicken Penne Pasta that combines tender chicken, colorful bell peppers, and a rich sauce for a comforting weeknight meal. This easy-to-make dish brings a taste of the South to your dinner table, perfect for satisfying cravings.
- Prep Time: 15 minutes
- Cook Time: 25 minutes
- Total Time: 40 minutes
- Yield: 4 servings 1x
Ingredients
- 8 ounces penne pasta
- 2 tablespoons olive oil
- 1 pound boneless, skinless chicken breasts, cut into bite-sized pieces
- 2 teaspoons Cajun seasoning
- 1 teaspoon garlic powder
- 1 teaspoon onion powder
- 1/2 teaspoon smoked paprika
- 1/2 teaspoon salt
- 1/4 teaspoon black pepper
- 1 medium onion, diced
- 1 red bell pepper, diced
- 1 green bell pepper, diced
- 3 cloves garlic, minced
- 1 cup heavy cream
- 1 cup chicken broth
- 1 cup grated Parmesan cheese
- 1/4 cup fresh parsley, chopped (for garnish)
Instructions
- Bring a large pot of salted water to a boil over high heat.
- Add the penne pasta to the boiling water and cook according to package instructions until al dente, usually about 10-12 minutes.
- Once cooked, reserve 1/2 cup of the pasta water, then drain the pasta in a colander and set aside.
- In a large mixing bowl, combine the chicken pieces with Cajun seasoning, garlic powder, onion powder, smoked paprika, salt, and black pepper. Toss until the chicken is evenly coated with the spices.
- Heat 2 tablespoons of olive oil in a large skillet over medium-high heat.
- Add the seasoned chicken to the skillet in a single layer. Cook for about 5-7 minutes, stirring occasionally, until the chicken is browned and cooked through. The internal temperature should reach 165°F (75°C).
- Once cooked, remove the chicken from the skillet and set aside on a plate.
- In the same skillet, add the diced onion, red bell pepper, and green bell pepper. Sauté for about 4-5 minutes, or until the vegetables are softened and the onion is translucent.
- Add the minced garlic to the skillet and cook for an additional 1-2 minutes, stirring frequently to prevent burning.
- Pour in the heavy cream and chicken broth into the skillet with the sautéed vegetables. Stir well to combine.
- Bring the mixture to a gentle simmer, allowing it to cook for about 3-4 minutes. This will help the flavors meld together.
- Gradually add the grated Parmesan cheese to the sauce, stirring continuously until the cheese is melted and the sauce is creamy. If the sauce is too thick, add a little of the reserved pasta water until you reach your desired consistency.
- Add the cooked chicken back into the skillet, stirring to coat it in the creamy sauce.
- Next, add the drained penne pasta to the skillet. Toss everything together until the pasta is well coated with the sauce and all ingredients are evenly distributed.
- Cook for an additional 2-3 minutes over low heat, allowing the pasta to absorb some of the sauce and heat through.
- Once everything is heated through, remove the skillet from the heat.
- Serve the Cajun Chicken Penne Pasta hot, garnished with freshly chopped parsley for a pop of color and added flavor.
- For an extra touch, you can sprinkle additional Parmesan cheese on top before serving.
Notes
- For a spicier dish, consider adding a pinch of cayenne pepper or using a spicier Cajun seasoning blend.
- Feel free to customize the vegetables based on your preference. Zucchini, mushrooms, or spinach can be great additions.
Leave a Comment